ROBO1 (Internal) blocking peptide

Species: Human

Specificity/Sensitivity: The peptide was used in the production of GTX89308.

Form: Lyophilized powder

Buffer (with preservative): Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservative.

Background: Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Region Sequence: C-GDVDLSNKINEMK

Full Name: roundabout guidance receptor 1

• Artikelnummer: GTX89308-PEP-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX89308-PEP-100
• Verpackungseinheit: 100 μg
• Mengeneinheit: STK
• Human Gene ID: 6091