Roscovitine, CAS 186692-46-6

p34/cdc2 inhibitor

Product Type: Inhibitor

CAS No.: 186692-46-6

MolecularFormula: C19H26N6O

Molecular Weight: 354,4

Source: Synthetic

Purity: >99% (TLC and HPLC); NMR (Conforms)

Solubility: May be dissolved in ethanol (10mg/mL); or DMSO (10mg/mL, warm)

Appearance: White to off-white solid

PubChem CID: 160355

Scientific Background: Roscovitine is a potent and selective inhibitor of cyclin-dependent kinases (CDKs). It is specifically selective for CDK1/cyclin B kinase, CDK2 and CDK5/p35. It inhibits M phase promoting factor kinase activity and affects calcium channel gating. It also stimulates neuronal growth.

References: 1. De Azevedo, et al. (1997) Eur. J. Biochem. 243(1-2): 518–526.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-472-2MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-472-2MG
• Verpackungseinheit: 2 mg
• Mengeneinheit: STK