RPI-1, CAS 269730-03-2

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 1,3-dihydro-3-[(4-hydroxyphenyl)methylene]-5,6-dimethoxy-2H-indol-2-one

Purity: ≥98%

Formula Markup: C17H15NO4

Formula Weight: 297.3

CAS Number: 269730-03-2

Notes: RPI-1 is an ATP-dependent RET kinase inhibitor. It has been shown to selectively inhibit the anchorage-independent growth of NIH3T3 cells transformed by the ret/ptc1 oncogene with an IC50 value of 0.97 µM.{32109} In a spontaneously metastasizing lung carcinoma xenograft mouse model, daily oral treatment with RPI-1 was reported to significantly reduce spontaneous lung metastases.{32108}

• Artikelnummer: CAY20384-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 20384-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK