Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 6-methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one
Purity: ≥98%
Formula Markup: C25H27N3O3
Formula Weight: 417.5
CAS Number: 300816-15-3
Notes: RS 504393 is a selective antagonist of the MCP-1 receptor CCR2 (IC50s = 89 nM and >100 μM for CCR2 and CCR1, respectively).{29459} It has been shown to inhibit MCP-1-stimulated chemotaxis (IC50 = 330 nM) and ischemia-reperfusion injury in kidneys.{29459,32283}