Product Description: (RS)-MCPG (alpha-MCPG) is a competitive and selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. (RS)-MCPG blocks theta-burst stimulation (TBS)-induced shifts in both juvenile and neonatal rat hippocampal neurons[1][2].
Applications: Neuroscience-Neuromodulation
Formula: C10H11NO4
References: [1]Yang B et al. Regulation of GABA Equilibrium Potential by mGluRs in Rat Hippocampal CA1 Neurons. PLoS One, 2015 Sep 21, 10(9):e0138215./[2]Fiona Yeuk-Lun Choi, et al. The effects of (RS)-MCPG on amphetamine-induced sensitization in neonatal rats.
CAS Number: 146669-29-6
Molecular Weight: 209.201
Compound Purity: 99.05
Research Area: Neurological Disease
Solubility: 1M NaOH : 100 mg/mL (ultrasonic;adjust pH to 10 with NaOH)/DMSO : 6 mg/mL (ultrasonic;warming)/H2O : < 0.1 mg/mL (ultrasonic;heat to 80°C)