Product Description: S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2), with IC50s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1. S29434 induces autophagy and inhibits QR2-mediated ROS production[1].
Applications: Neuroscience-Neuromodulation
Formula: C21H18N4O3
References: [1]Boutin JA, et al. S29434, a Quinone Reductase 2 Inhibitor: Main Biochemical and Cellular Characterization. Mol Pharmacol. 2019 Mar;95(3):269-285.
CAS Number: 874484-20-5
Molecular Weight: 374.39
Compound Purity: 99.25
Research Area: Neurological Disease
Solubility: DMSO : 19.29 mg/mL (ultrasonic)
Target: Autophagy