Shelf life (days): 1460.0
Formulation: A solid
Formal Name: N1-hydroxy-N8-(phenyl-2,3,4,5,6-d5)-octanediamide
Purity: ≥99% deuterated forms (d1-d5)
Formula Markup: C14H15D5N2O3
Formula Weight: 269.4
CAS Number: 1132749-48-4
Notes: SAHA-d5 contains five deuterium atoms at the 2, 3, 4, 5, and 6 positions. It is intended for use as an internal standard for the quantification of SAHA (suberoylanilide hydroxamic acid; Item No. 10009929) by GC- or LC-MS. SAHA is a histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. It inhibits class I, II, and IV HDACs at 50-200 nM and arrests cell growth in a wide variety of transformed cells in culture at 2.5-5.0 µM.{14739}