Salermide, CAS 1105698-15-4

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-[3-[[(2-hydroxy-1-naphthalenyl)methylene]amino]phenyl]-a-methyl-benzeneacetamide

Purity: ≥98%

Formula Markup: C26H22N2O2

Formula Weight: 394.5

CAS Number: 1105698-15-4

Notes: The sirtuins (SIRTs) are a family of NAD+-dependent histone deacetylases involved in gene regulation that is relevant to, e.g., longevity, cancer, gene regulation, energy homeostasis, and apoptosis.{15106,16291} Salermide is an inhibitor of SIRT1 and SIRT2, causing tumor-specific apoptotic cell death.{16699} In MOLT4 leukemia cells, salermide causes 90% apoptosis within 72 hours (IC50 ~20 μM) by reactivating proapototic genes that are repressed by SIRT1.{16699}

• Artikelnummer: CAY13178-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 13178-100
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK