Shelf life (days): 1460.0
Formulation: A solid
Formal Name: aR-[[(2-phenyl-4-quinolinyl)carbonyl]amino]-benzeneacetic acid, methyl ester
Purity: ≥98%
Formula Markup: C25H20N2O3
Formula Weight: 396.43798
CAS Number: 174635-53-1
Notes: An NK3 receptor antagonist (Ki = 0.013 µM); selective for NK3 over NK1 and NK2 receptors (Kis = >100 and 1.221 µM, respectively); inhibits senktide-induced contractions in isolated rabbit iris sphincter muscle preparations (Kb = 43 nM); inhibits substance P-induced contraction of longitudinal and circular smooth muscles isolated from rabbit duodenum, jejunum, or ileum at 1 µM