Product Description: SB 239063 is a potent, selective and orally active p38 MAPK inhibitor, exhibits an IC50 of 44 nM for recombinant purified human p38α, with equipotent inhibitory activity against p38α and p38β. SB 239063 has no effect on p38γ or p38δ. With anti-asthma activity and also be used to enhance memory which is impaired due to aging or medical conditions, such as, AD[1][2].
Applications: COVID-19-immunoregulation
Formula: C20H21FN4O2
References: [1]Underwood DC, et al. SB 239063, a potent p38 MAP kinase inhibitor, reduces inflammatory cytokine production, airways eosinophil infiltration, and persistence. J Pharmacol Exp Ther. 2000 Apr;293(1):281-8./[2]Matthew Huentelman, et al. Methods of treating memory loss and enhancing memory performance. US 20120245188 A1.
CAS Number: 193551-21-2
Molecular Weight: 368.40
Compound Purity: 99.61
Research Area: Inflammation/Immunology
Solubility: DMSO : 33.33 mg/mL (ultrasonic)
Target: Autophagy;p38 MAPK
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