Seltorexant, CAS 1293281-49-8

Product Description: Seltorexant (JNJ-42847922) is an orally active, high-affinity, and selective orexin-2 receptor (OX2R) antagonist (pKi values of 8.0 and 8.1 for human and rat OX2R). Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain[1].

Applications: Neuroscience-Neuromodulation

Formula: C21H22FN7O

References: [1]Bonaventure P, et al. Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia. J Pharmacol Exp Ther. 2015 Sep;354(3):471-82.

CAS Number: 1293281-49-8

Molecular Weight: 407.44

Compound Purity: 99.86

Research Area: Neurological Disease; Endocrinology

Solubility: DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Orexin Receptor (OX Receptor)

• Artikelnummer: MEXHY-109012-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-109012-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK