SEN12333, CAS 874450-44-9

Product Description: SEN 12333 (WAY-317538) is a potent, selective and orally active α7 nAChR agonist. SEN12333 displays high affinity for the rat α7 nAChRs expressed in GH4C1 cells (K>i=260 nM) and acts as full agonist in functional Ca2+ flux studies (EC50=1.6 μM). SEN 12333 is used for AD and schizophrenia research[1].

Applications: Neuroscience-Neuromodulation

Formula: C20H25N3O2

References: [1]Corinne Beinat, et al. The Recent Development of α7 Nicotinic Acetylcholine Receptor (nAChR) Ligands as Therapeutic Candidates for the Treatment of Central Nervous System (CNS) Diseases.Curr Pharm Des. 2016;22(14):2134-51./[2]Renza Roncarati, et al. Procognitive and neuroprotective activity of a novel alpha7 nicotinic acetylcholine receptor agonist for treatment of neurodegenerative and cognitive disorders. J Pharmacol Exp Ther. 2009 May;329(2):459-68.

CAS Number: 874450-44-9

Molecular Weight: 339.43

Compound Purity: 98.45

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: nAChR

• Artikelnummer: MEXHY-107678-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-107678-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK