SerpinB3 Monoclonal Antibody

Target Synonym: HsT;SSCA;Member;SERPINB;serpin B;SERPINB3;HsT1196;SCC;SCCA-1;SCCA-PD;SCCA1;SSCA1;T4-A;serpin B3;Clade B(ovalbumin);Member 3;Serpin Peptidase Inhibitor;SCCA;Serpin Peptidase Inhibitor;T4-A;clade B (ovalbumin);Clade B(ovalbumin);Protein T4-A;serine (or cysteine) proteinase inhibitor;Squamous cell carcinoma antigen 1

Background: Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. It may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. It also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).

Immunogen: Recombinant Human SerpinB3 Protein

Buffer: 0.2 μm filtered solution in PBS

Dilution: WB 1:500-1:2000

Calculated MW: 45 kDa

Observed MW: 45 kDa

• Artikelnummer: ELSAN200226P-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: AN200226P-100
• Verpackungseinheit: 100μL
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Recombinant
• Methode: Western Blotting
• Isotyp: IgG2a
• Wirt: Mouse
• Konjugat: Unconjugated