SGI-1027, CAS 1020149-73-8

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-[4-[(2-amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)-benzamide

Purity: ≥98%

Formula Markup: C27H23N7O

Formula Weight: 461.5

CAS Number: 1020149-73-8

Notes: SGI-1027 is an inhibitor of the DNA methyltransferases DNMT1, DNMT3A, and DNMT3B (IC50s = 12.5, 8, and 7.5 μM, respectively, with Poly(dI-dC) as the substrate).{20127} It has been shown to cause the degradation of DNMT1 and to reactivate silenced tumor suppressor genes by reducing CpG island hypermethylation.{20127}

• Artikelnummer: CAY11165-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 11165-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK