SHIN1, CAS 2146095-85-2

Product Description: SHIN1 (RZ-2994) is a human serine hydroxymethyltransferse 1 and 2 (SHMT1/2) inhibitor with IC50s of 5 and 13 nM, respectively, in an in vitro assay.

Applications: Cancer-programmed cell death

Formula: C24H24N4O2

References: [1]Ducker GS, et al. Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11404-11409.

CAS Number: 2146095-85-2

Molecular Weight: 400.47

Compound Purity: 99.43

Research Area: Cancer

Solubility: DMSO : 66.67 mg/mL (ultrasonic)

Target: SHMT

• Artikelnummer: MEXHY-112066-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-112066-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK