Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 6-chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol, monohydrobromide
Purity: ≥98%
Formula Markup: C16H16ClNO2 / HBr
Formula Weight: 370.7
CAS Number: 67287-39-2
Notes: (±)-SKF 81297 is a selective agonist of the dopamine D1-like receptor (Ki = 1.9 nM).{24103} It demonstrates comparatively lower binding affinity for the dopamine D2, dopamine D3, serotonin 5-HT2A, and adrenergic α2 receptors (Kis = 1,272, >10,000, 955, and 509 nM, respectively).{24103} Activation of dopamine D1-like receptors by selective agonists such as (±)-SKF 81297 have been implicated in initiating a cascade of signaling events leading to reward-related incentive learning.{24104}