SLF, CAS 195513-96-3

Product Description: SLF is a synthetic ligand for FK506-binding protein (FKBP) with an affinity of 3.1 μM for FKBP51 and an IC50 of 2.6 μM for FKBP12. SLF can be used in the synthesis of PROTAC[1][2][3].

Applications: Cancer-programmed cell death

Formula: C30H40N2O6

References: [1]Kolos JM, et al. FKBP Ligands-Where We Are and Where to Go? Front Pharmacol. 2018 Dec 5;9:1425./[2]Wu X, et al. Creating diverse target-binding surfaces on FKBP12: synthesis and evaluation of a rapamycin analogue library. ACS Comb Sci. 2011 Sep 12;13(5):486-95./[3]Zhang X, et al. Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16. Nat Chem Biol. 2019 Jul;15(7):737-746.

CAS Number: 195513-96-3

Molecular Weight: 524.65

Compound Purity: 99.91

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)

Target: FKBP;Ligands for Target Protein for PROTAC

• Artikelnummer: MEXHY-114872-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-114872-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK