Product Description: SLU-PP-332 is a pan-Estrogen Receptor/ERR agonist with EC50 values of 98, 230 and 430 nM for ERRα, ERRβ and ERRγ, respectively. SLUPP-332 enhances mitochondrial function and cellular respiration in skeletal muscle cell lines. SLU-PP-332 has the potential to study metabolic diseases as well as improve muscle function[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C18H14N2O2
References: [1]Billon C, et al. Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity. ACS Chem Biol. 2023 Apr 21;18(4):756-771./[2]Nasri H. New hopes on" SLU-PP-332" as an effective agent for weight loss with indirect kidney protection efficacy; a nephrology point of view[J]. Journal of Renal Endocrinology, 2024, 10(1): e25143-e25143./[3]Billon C, et al. A Synthetic ERR Agonist Alleviates Metabolic Syndrome. J Pharmacol Exp Ther. 2024 Jan 17;388(2):232-240.
CAS Number: 303760-60-3
Molecular Weight: 290.32
Compound Purity: 99.82
Research Area: Metabolic Disease
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Estrogen Receptor/ERR
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