Product Description: SMS1-IN-1, compound SAPA 1j, is a novel and the most potent sphingomyelin synthase 1 (SMS1) inhibitor with an IC50 value of 2.1 μM. SMS1-IN-1 has the potential for the treatment of atherosclerosis[1].
Applications: COVID-19-immunoregulation
Formula: C23H23BrN2O4S
References: [1]Li YL, et al. Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors.Bioorg Med Chem. 2015 Sep 15;23(18):6173-84.
CAS Number: 1807943-38-9
Molecular Weight: 503.41
Compound Purity: 99.44
Research Area: Inflammation/Immunology
Solubility: DMSO : 250 mg/mL (ultrasonic)
Target: Phospholipase