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CAS Number: 86639-52-3
Description: SN-38 is an anti-tumor drug that is often linked to ADCs to be directly delivered to cells. It is also the active metabolite of the drug, irinotecan. Its mechanism of action is inhibition of DNA topoisomerase I, halting DNA synthesis and causing single-strand breaks in DNA.
Format: Solid
Purity: ≥98%
Storage Stability: At least 6 months at -20°C.
Warnings: Avoid freeze/thaw cycles. See SDS for additional warnings and handling.