Product Description: Sodium tetradecyl sulfate (Tergitol 4) is a novel scleroembolic agent and an apoptosis inducer. Sodium tetradecyl sulfate can be used for research on varicose veins and vascular malformation diseases[1][2][3].
Applications: Cancer-programmed cell death
Formula: C14H29NaO4S
References: [1]Connor DE, et al. Sirolimus and propranolol inhibit endothelial proliferation while detergent sclerosants induce endothelial activation, microparticle release and apoptosis in vitro. Phlebology. 2020 Sep;35(8):566-575./[2]Zehtabi F, et al. Chitosan-Sodium Tetradecyl Sulfate Hydrogel: Characterization and Preclinical Evaluation of a Novel Sclerosing Embolizing Agent for the Treatment of Endoleaks. Cardiovasc Intervent Radiol. 2017 Apr;40(4):576-584. /[3]Morsiani E, et al. Effect of intravenous and intraperivenous injections of sclerosants (sodium tetradecyl sulfate and hydroxy polyethoxy dodecan) on the rat femoral vein. Res Exp Med (Berl). 1987;187(6):439-49. /[4]Zimmet SE. The prevention of cutaneous necrosis following extravasation of hypertonic saline and sodium tetradecyl sulfate. J Dermatol Surg Oncol. 1993 Jul;19(7):641-6. /[5]Frullini A, et al. Significant endothelin release in patients treated with foam sclerotherapy. Dermatol Surg. 2012 May;38(5):741-7.
CAS Number: 139-88-8
Molecular Weight: 316.43
Research Area: Cancer; Inflammation/Immunology; Cardiovascular Disease
Solubility: H2O : 62.5 mg/mL (ultrasonic)
Target: Apoptosis
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