SR 144528, CAS 192703-06-3

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,2S,4R)-1,3,3-trimethylbicyclo[2.2.1]hept-2-yl]-1H-pyrazole-3-carboxamide

Purity: ≥98%

Formula Markup: C29H34ClN3O

Formula Weight: 476.1

CAS Number: 192703-06-3

Notes: SR 144528 is a cannabinoid 2 (CB2) receptor antagonist (Ki = 0.6 nM).{7912} It is selective for CB2 over CB1 receptors in CHO cells expressing the human receptors (Ki = 437 nM).{17199} SR 144528 reverses CP 55,940-induced inhibition of forskolin-induced adenylyl cyclase activity in CHO cells expressing human CB2 receptors (EC50 = 10 nM). SR 144528 (0.01 mg/kg) reduces paw swelling in a mouse model of carrageenan-induced paw edema.{14732}

• Artikelnummer: CAY9000491-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 9000491-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK