Statil, CAS 72702-95-5

Statil, CAS 72702-95-5
Artikelnummer
CAY19189-25
Verpackungseinheit
25 mg
Hersteller
Cayman Chemical

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Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 3-[(4-bromo-2-fluorophenyl)methyl]-3,4-dihydro-4-oxo-1-phthalazineacetic acid

Purity: ≥98%

Formula Markup: C17H12BrFN2O3

Formula Weight: 391.2

CAS Number: 72702-95-5

Notes: Statil is an aldose reductase inhibitor that blocks the conversion of glucose to sorbitol. It demonstrates selectivity for aldose reductase 2 over aldose reductase 1 with Ki values of 7.7 nM and 60 µM, respectively.{31161} Statil has been shown to prevent diabetes-induced alterations of the cardiovascular system in 14-day streptozotocin-diabetic rats.{31160} Aldose reductase inhibition by statil has also been used to impair the synthesis of prostaglandin F2α by human cultured preadipocytes.{31159}
Mehr Informationen
Artikelnummer CAY19189-25
Hersteller Cayman Chemical
Hersteller Artikelnummer 19189-25
Verpackungseinheit 25 mg
Mengeneinheit STK
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