STF-62247, CAS 315702-99-9

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N-(3-methylphenyl)-4-(4-pyridinyl)-2-thiazolamine

Purity: ≥98%

Formula Markup: C15H13N3S

Formula Weight: 267.3

CAS Number: 315702-99-9

Notes: STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM).{17445} It significantly reduces the growth rate of tumors formed from VHL-deficient cells in mice.{17445,17446,17447} STF-62247 induces cytotoxicity in VHL-positive RCC cells only at higher concentrations (IC50 = 16 μM).{17445}

• Artikelnummer: CAY13084-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 13084-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK