STM2457, CAS 2499663-01-1

Product Description: STM2457 is a first-in-class, highly potent, selective and orally active METTL3 inhibitor with an IC50 of 16.9 nM. STM2457 can be used for the research of acute myeloid leukaemia (AML)[1][2].

Applications: Cancer-programmed cell death

Formula: C25H28N6O2

References: [1]Wesley Peter Blackaby, et al. Mettl3 inhibitory compounds. WO2020201773A1./[2]Eliza Yankova, et al. Small molecule inhibition of METTL3 as a strategy against myeloid leukaemia. Nature. 2021 Apr 26.

CAS Number: 2499663-01-1

Molecular Weight: 444.53

Compound Purity: 99.87

Research Area: Cancer

Solubility: DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Apoptosis;METTL3

• Artikelnummer: MEXHY-134836-100
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-134836-100
• Verpackungseinheit: 100 mg
• Mengeneinheit: STK