Product Description: SU11652 is a potent receptor tyrosine kinase (RTK) inhibitor. SU11652 also inhibits several members of the split kinase family of RTKs, including VEGFR, FGFR, PDGFR, and Kit. SU11652 can be uesd for spontaneous cancers expressing Kit mutations research[1].
Applications: Cancer-Kinase/protease
Formula: C22H27ClN4O2
References: [1]Liao AT, et al. Inhibition of constitutively active forms of mutant kit by multitargeted indolinone tyrosine kinase inhibitors. Blood. 2002;100(2):585-593.
CAS Number: 326914-10-7
Molecular Weight: 414.93
Compound Purity: 99.06
Research Area: Cancer
Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Apoptosis;c-Kit;FGFR;PDGFR;VEGFR