Product Description: Sulfatroxazole-d4 (Isosulfafurazole-d4) is the deuterium labeled Sulfatroxazole (HY-105829)[1]. Sulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of ETA receptor (IC50 of 0.26 μM)[2].
Formula: C11H9D4N3O3S
References: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216./[2]Stein P D, et al. Discovery and structure-activity relationships of sulfonamide ETA-selective antagonists[J]. Journal of medicinal chemistry, 1995, 38(8): 1344-1354.
Molecular Weight: 271.33
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Endothelin Receptor;Isotope-Labeled Compounds