Product Description: Sulphostin is a covalent inhibitor of dipeptidyl peptidase 4 (DPP4), dipeptidyl peptidase 9 (DPP9), and dipeptidyl peptidase 8 (DPP8) with IC50 values of 79, 1392, 6930 nM, respectively. Sulphostin causes phosphosulfamate modification, irreversibly inhibits the enzyme activity. Sulphostin can be used for inflammation and cancer study[1].
Applications: COVID-19-immunoregulation
Formula: C5H13N4O5PS
References: [1]Sewald L, et al. Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors. Nat Commun. 2025 Apr 3;16(1):3208.
Molecular Weight: 272.22
Research Area: Cancer; Inflammation/Immunology
Target: Dipeptidyl Peptidase