Product Description: SY-LB-35 is a potent bone morphogenetic protein (BMP) receptor agonist. SY-LB-35 can stimulate significant increases in cell number and cell viability in the C2C12 myoblast cell line, and causes shifts towards the S and G2/M phases of the cell cycle. SY-LB-35 stimulates canonical Smad and non-canonical PI3K/Akt, ERK, p38 and JNK intracellular signaling pathways[1].
Applications: Cancer-Kinase/protease
Formula: C15H11N3O
References: [1]Najafi S, et al. Discovery of a novel class of benzimidazoles as highly effective agonists of bone morphogenetic protein (BMP) receptor signaling. Sci Rep. 2022 Jul 15;12(1):12146.
CAS Number: 2603461-70-5
Molecular Weight: 249.27
Compound Purity: 98.0
Research Area: Others
Solubility: DMSO : 100 mg/mL (ultrasonic)
Target: Akt;ERK;JNK;PI3K;TGF-beta/Smad