Product Description: Tandospirone (SM-3997) is a potent and selective 5-HT1A receptor partial agonist, with a Ki of 27 nM. Tandospirone has anxiolytic and antidepressant activities. Tandospirone can be used for the research of the central nervous system disorders and the underlying mechanisms[1][2][3].
Applications: Neuroscience-Neuromodulation
Formula: C21H29N5O2
References: [1]Hamik A, et al. Analysis of tandospirone (SM-3997) interactions with neurotransmitter receptor binding sites. Biol Psychiatry. 1990 Jul 15;28(2):99-109./[2]Xuefei Huang, et al. Role of tandospirone, a 5-HT1A receptor partial agonist, in the treatment of central nervous system disorders and the underlying mechanisms. Oncotarget. 2017 Nov 24; 8(60): 102705–102720./[3]Kyoko Nishitsuji, et al. The pharmacokinetics and pharmacodynamics of tandospirone in rats exposed to conditioned fear stress. Eur Neuropsychopharmacol. 2006 Jul;16(5):376-82.
CAS Number: 87760-53-0
Molecular Weight: 383.49
Compound Purity: 99.41
Research Area: Neurological Disease
Solubility: DMSO : 16.67 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL
Target: 5-HT Receptor
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