TAS-119, CAS 1453099-83-6

Description: TAS-119 (TAS-2104) is an orally available, selective and potent inhibitor of Aurora A with an IC50 of 1.0 nM.TAS-119 also inhibits Aurora B with an IC50 of 95 nM.TAS-119 has a higher affinity for Aurora A than for Aurora B.TAS-119 exhibits potent antitumor activity and potential antimitotic activity. TAS-119 has potent anti-tumor activity and potential anti-mitotic activity.

CAS Number: 1453099-83-6

Formula: C23H22Cl2FN5O3

Molecular Weight: 506,36

References: Sootome H, et al. Aurora A Inhibitor TAS-119 Enhances Antitumor Efficacy of Taxanes In Vitro and In Vivo: Preclinical Studies as Guidance for Clinical Development and Trial Design. Mol Cancer Ther. 2020;19(10):1981-199

• Artikelnummer: TGMT34787-1mL
• Hersteller: TargetMol Chemicals
• Hersteller Artikelnummer: T34787-1mL
• Verpackungseinheit: 1 mL
• Mengeneinheit: STK