Product Description: Taurocholic acid sodium (Sodium taurocholate) has marked bioactive effects such as an inhibitory potential against hepatic artery ligation induced biliary damage by upregulation of VEGF-A expression. Taurocholic acid sodium has immunoregulation effect[1].
Applications: COVID-19-immunoregulation
Formula: C26H44NNaO7S
Citations: Adv Healthc Mater. 2024 Dec 4:e2402773./FASEB J. 2022 May;36(5):e22305./Research Square Preprint. 2024 Feb 13./Sci Rep. 2024 Oct 31;14(1):26216./Antiviral Res. 2019 Jun 27;169:104544./Food Funct. 2024 Apr 11./Food Funct. 2024 Sep 11./Int Immunopharmacol. 2024 Dec 10:145:113739./J Transl Med. 2024 Dec 20;22(1):1124./Nature. 2024 Dec 18./Placenta. 2024 Feb 8:148:20-30./Plant Commun. 2024 Nov 4:101181./Research (Wash D C). 2022 Nov 2;2022:9784081./Research Square Print. 2022 Aug./Science. 2024 Mar 22;383(6689):eadj4591./Biomolecules. 2022, 12(8), 1063./RSC Adv. 2018 8:8469-8483./SSRN. 2022 Jan 26.
References: [1]Caiyun Wang, et al. Effects of taurocholic acid on immunoregulation in mice. Int Immunopharmacol. 2013 Feb;15(2):217-22./[2]Xun Z,et al. Taurocholic acid inhibits the response to interferon-α therapy in patients with HBeAg-positive chronic hepatitis B by impairing CD8+ T and NK cell function. Cell Mol Immunol. 2021 Feb;18(2):461-471. /[3]Glaser S, et al. Taurocholic acid prevents biliary damage induced by hepatic artery ligation in cholestatic rats. Dig Liver Dis. 2010 Oct;42(10):709-17.
CAS Number: 145-42-6
Molecular Weight: 537.68
Compound Purity: 98.0
Research Area: Inflammation/Immunology
Solubility: DMSO : 175 mg/mL (ultrasonic)/H2O : 100 mg/mL (ultrasonic)
Target: Endogenous Metabolite;VEGFR
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