Product Description: TCS7010 is a potent and highly selective Aurora A inhibitor with with an IC50 of 3.4 nM.
Applications: Cancer-Kinase/protease
Formula: C31H31ClFN7O2
References: [1]Aliagas-Martin I, Burdick D, Corson L, Dotson J, Drummond J, Fields C, Huang OW, Hunsaker T, Kleinheinz T, Krueger E, Liang J, Moffat J, Phillips G, Pulk R, Rawson TE, Ultsch M, Walker L, Wiesmann C, Zhang B, Zhu BY, Cochran AG.A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora B.J Med Chem. 2009 May 28;52(10):3300-7.
CAS Number: 1158838-45-9
Molecular Weight: 588.08
Compound Purity: 99.82
Research Area: Cancer
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: Apoptosis;Aurora Kinase