Shelf life (days): 1460.0
Formulation: A solid
Formal Name: 1-(2-deoxy-ß-L-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
Purity: ≥98%
Formula Markup: C10H14N2O5
Formula Weight: 242.2
CAS Number: 3424-98-4
Notes: Telbivudine is a β-L-nucleoside analog of thymidine (Item No. 20519) that has antiviral activity.{42834,42835} It is active against hepatitis B virus (HBV) in 2.2.15 cells (EC50 = 0.19 μM).{42835} Telbivudine is selective for HBV over HIV-1, herpes simplex virus-1 (HSV-1), HSV-2, and influenza A and B (EC50s = >100 μM). It reduces serum viral load in a woodchuck model of chronic HBV infection in a dose-dependent manner. Formulations containing telbivudine have been used in the treatment of chronic HBV infection.