Product Description: Temozolomide acid is a carboxylic acid derivative of Temozolomide (HY-17364) with anticancer activity. Temozolomide is a DNA alkylating agent, methylating the guanine and adenine bases of DNA, causing breaks in DNA double strand, cell cycle arrest, and eventually cell death. Temozolomide acid is promising for research of glioblastoma and brain cancer[1].
Applications: Cancer-programmed cell death
Formula: C6H5N5O3
References: [1]Helal DO, et al. A natural protein based platform for the delivery of Temozolomide acid to glioma cells. Eur J Pharm Biopharm. 2021 Dec;169:297-308.
CAS Number: 113942-30-6
Molecular Weight: 195.14
Compound Purity: 99.92
Research Area: Cancer
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: DNA/RNA Synthesis