Product Description: Terephthalic acid is one isomer of the three phthalic, a precursor to the polyester PET, used to make clothing and plastic bottles.
Applications: Metabolism-sugar/lipid metabolism
Formula: C8H6O4
References: [1]Heck HD, et al. The induction of bladder stones by terephthalic acid, dimethyl terephthalate, and melamine (2,4,6-triamino-s-triazine) and its relevance to risk assessment. Regul Toxicol Pharmacol. 1985 Sep;5(3):294-313./[2]Saito M, et al. CENP-50 is required for papilloma development in the two-stage skin carcinogenesis model. Cancer Sci. 2020 Aug;111(8):2850-2860./[3]Cui L, et al. Deregulation of the p16-cyclin D1/cyclin-dependent kinase 4-retinoblastoma pathway involved in the rat bladder carcinogenesis induced by terephthalic acid-calculi. Urol Res. 2006 Oct;34(5):321-8./[4]Ball GL, et al. Toxicological review and oral risk assessment of terephthalic acid (TPA) and its esters: A category approach. Crit Rev Toxicol. 2012 Jan;42(1):28-67.
CAS Number: 100-21-0
Molecular Weight: 166.13
Compound Purity: 99.99
Research Area: Cancer
Solubility: DMSO : 20 mg/mL (ultrasonic)
Target: Endogenous Metabolite
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