Teriflunomide impurity 3, CAS 1011244-72-6

Product Description: Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor with an IC50 of 30 μM. Teriflunomide impurity 3 is less active against COX-2 (IC50>100 μM)[1].

Applications: COVID-19-immunoregulation

Formula: C14H11F3N2O

References: [1]Hiroki Kakuta, et al. Cyclooxygenase-1-selective inhibitors are attractive candidates for analgesics that do not cause gastric damage. design and in vitro/in vivo evaluation of a benzamide-type cyclooxygenase-1 selective inhibitor. J Med Chem. 2008 Apr 24;51(8):2400-11.

CAS Number: 1011244-72-6

Molecular Weight: 280.25

Compound Purity: 99.75

Research Area: Inflammation/Immunology

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: COX

• Artikelnummer: MEXHY-134753-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-134753-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK