Clone Name: MSVA-403R
Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.
Application Note: IHC-P: 1:100 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Form: Liquid
Buffer (with preservative): 10mM PBS, BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format), sodium azide.
Concentration: 37.5 μg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Uniprot ID: P19532
Antigen Species: Human
Immunogen: Recombinant human TFE3 fragment
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: transcription factor binding to IGHM enhancer 3
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