Shelf life (days): 1460.0
Formulation: A crystalline solid
Formal Name: 2-methyl-5-(1-methylethyl)-1,4-benzenediol
Purity: ≥98%
Formula Markup: C10H14O2
Formula Weight: 166.21696
CAS Number: 2217-60-9
Notes: Thymohydroquinone is a quinone that has been found in N. sativa seeds and has diverse biological activities.{47529,47530} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) free radicals in a cell-free assay (IC50 = 2.4 μg/ml) and has a Trolox equivalent value of 2.6 in an oxygen radical absorbance capacity (ORAC) assay when used at concentrations ranging from 1.6 to 6.4 μg/ml.{47529} Thymohydroquinone inhibits growth of A2780, OVCAR-8, and CIS-A2780 ovarian cancer cells (IC50s = 3.1, 8.9, and 9.8 μM, respectively), as well as immortalized human ovarian epithelial cells (IC50 = 14 μM).{47530} It is also active against P. falciparum in vitro (IC50 = 15.9 μM).
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