Tienilic Acid, CAS 40180-04-9

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: [2,3-dichloro-4-(2-thienylcarbonyl)phenoxy]-acetic acid

Purity: ≥99%

Formula Markup: C13H8Cl2O4S

Formula Weight: 331.2

CAS Number: 40180-04-9

Notes: Cytochrome P450 enzymes function to metabolize both endogenous and exogenous compounds. Both the 3A and 2C isoforms are present in human liver of which CYP2C9 seems most highly expressed.{14151} Tienilic acid is a specific suicide substrate for CYP2C9 and CYP2C10 whereby its oxidation inactivates the enzyme.{14150,14152} The time required to inactivate one half of the CYP2C10 enzyme at the maximal rate (t½max) is 3.4 minutes, with a dissociation constant (Kd) value of 4.3 µM.{14152}

• Artikelnummer: CAY10008517-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10008517-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK