TLQP 21 (trifluoroacetate salt)

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: L-threonyl-L-leucyl-L-glutaminyl-L-prolyl-L-prolyl-L-alanyl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-arginyl-L-histidyl-L-phenylalanyl-L-histidyl-L-histidyl-L-alanyl-L-leucyl-L-prolyl-L-prolyl-L-alanyl-L-arginine, trifluoroacetate salt

Amino Acids: TLQPPASSRRRHFHHALPPAR-OH

Purity: ≥95%

Formula Markup: C107H170N40O26 / XCF3COOH

Formula Weight: 2432.8

Notes: A neuropeptide and fragment of VGF; selectively activates C3aR (EC50 = 83.6 nM in CHO cells expressing the human receptor) over C5a1 and C5a2 at 10 µM; induces phosphorylation of ERK1/2 in primary mouse BMDMs (EC50 = 96.5 nM); induces increases in intracellular calcium in primary mouse BMDMs, which can be inhibited by monoclonal antibodies targeting gC1qR; intraplantar hind paw injection of TLQP 21-activated macrophages induces mechanical hypersensitivity in rats; decreases food intake and body weight in hamsters at 25 µg/animal, i.c.v.; increases serum LH levels in pre-pubertal female rats when administered intraperitoneally but not intracerebroventricularly

• Artikelnummer: CAY36864-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36864-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK