Topiramate, CAS 97240-79-4

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: 2,3:4,5-bis-O-(1-methylethylidene)-ß-D-fructopyranose, 1-sulfamate

Purity: ≥98%

Formula Markup: C12H21NO8S

Formula Weight: 339.4

CAS Number: 97240-79-4

Notes: Topiramate is a sugar sulfamate with anticonvulsant activity.{18290} It inhibits carbonic anhydrase in intact human erythrocytes (Ki = ~200 μM), as well as blocks sodium and calcium channels and kainate-induced currents in vitro.{18290,32575,48075} It also increases GABAA receptor-mediated chloride ion flux.{48075} Topiramate inhibits hind-limb tonic-extensor seizures in the maximal electroshock seizure test in mice (ED50 = 39 mg/kg, p.o.).{18290} Formulations containing topiramate have been used in the treatment of epilepsy and prophylaxis of migraine headaches.

• Artikelnummer: CAY13623-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 13623-50
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK