trans-AUCB, CAS 885012-33-9

Product Description: trans-AUCB (t-AUCB) is a potent, orally active and selective soluble epoxide hydrolase (sEH) inhibitor with IC50s of 1.3 nM, 8 nM, 8 nM for hsEH, mouse sEH and rat sEH, respectively. trans-AUCB has anti-glioma activity[1][2].

Applications: Neuroscience-Neuromodulation

Formula: C24H32N2O4

References: [1]Li J, et al. t-AUCB, an improved sEH inhibitor, suppresses human glioblastoma cell growth by activatingNF-κB-p65. J Neurooncol. 2012 Jul;108(3):385-93./[2]Liu JY, et al. Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murinemodel of inflammation. Br J Pharmacol. 2009 Jan;156(2):284-96.

CAS Number: 885012-33-9

Molecular Weight: 412.52

Compound Purity: 98.16

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Epoxide Hydrolase

• Artikelnummer: MEXHY-113974-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-113974-10.1
• Verpackungseinheit: 10 mM/1 ml
• Mengeneinheit: STK