Trapidil, CAS 15421-84-8

Shelf life (days): 1460.0

Formulation: A crystalline solid

Formal Name: N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

Purity: ≥98%

Formula Markup: C10H15N5

Formula Weight: 205.2598

CAS Number: 15421-84-8

Notes: Trapidil is an inhibitor of PDGF-induced activity and an antiplatelet agent.{61303,54852} It inhibits PDGF-induced proliferation of U251MG glioma cells and isolated rat aortic smooth muscle cells in a concentration-dependent manner. Trapidil (1 mM) inhibits platelet aggregation induced by ADP, arachidonic acid (Item Nos. 90010 / 90010.1 / 10006607), or U-46619 (Item No. 16450) in washed isolated human platelets.{54853} It reduces increases in intimal thickness and prevents restenosis induced by balloon angioplasty in rabbits fed a high-cholesterol diet when administered at a dose of 30 mg/kg.{54854}

• Artikelnummer: CAY33496-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33496-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK