Trelagliptin-13C-d3, CAS 2707203-34-5

Shelf life (days): 1460.0

Formulation: A solid

Formal Name: (R)-2-((6-(3-aminopiperidin-1-yl)-3-(methyl-13C-d3)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile

Purity: ≥99% deuterated forms (d1-d3)

Formula Markup: C17[13C]H17D3FN5O2

Formula Weight: 361.4

CAS Number: 2707203-34-5

Notes: Trelagliptin-13C-d3 is intended for use as an internal standard for the quantification of trelagliptin (Item No. 18504) by GC- or LC-MS. Trelagliptin is an inhibitor of dipeptidyl peptidase 4 (DPP-4; IC50 = 4 nM).{29892} It is greater than 10,000-fold selective for DPP-4 over isopeptidases. Trelagliptin (7 mg/kg) inhibits plasma DPP-4 activity and reduces postprandial plasma insulin levels in Zucker fa/fa rats. Formulations containing trelagliptin have been used in the treatment of type 2 diabetes mellitus.

• Artikelnummer: CAY28203
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 28203-1
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung