Product Description: Tricin is a natural flavonoid found in large amounts in wheat. Tricin inhibits HCMV replication by inhibiting CDK9. Tricin inhibits the proliferation and invasion of C6 glioma cells by upregulating the expression of FAK-targeting microRNA-7 [1][2][3][1][2][3][4][5].
Applications: Cancer-programmed cell death
Formula: C17H14O7
References: [1]Itoh A, et al. Tricin inhibits the CCL5 induction required for efficient growth of human cytomegalovirus. Microbiol Immunol. 2018 May;62(5):341-347./[2]Sadanari H, et al. The anti-human cytomegalovirus drug tricin inhibits cyclin-dependent kinase 9. FEBS Open Bio. 2018 Feb 20;8(4):646-654./[3]Chung DJ, et al. Inhibition of the Proliferation and Invasion of C6 Glioma Cells by Tricin via the Upregulation of Focal-Adhesion-Kinase-Targeting MicroRNA-7. J Agric Food Chem. 2018 Jul 5;66(26):6708-6716./[4]Yazawa K, et al. Anti-influenza virus activity of tricin, 4',5,7-trihydroxy-3',5'-dimethoxyflavone. Antivir Chem Chemother. 2011 Aug 23;22(1):1-11./[5]Oyama T, et al. Dietary tricin suppresses inflammation-related colon carcinogenesis in male Crj: CD-1 mice. Cancer Prev Res (Phila). 2009 Dec;2(12):1031-8.
CAS Number: 520-32-1
Molecular Weight: 330.29
Compound Purity: 99.87
Research Area: Cancer; Infection
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: CMV
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