Product Description: Tuvusertib (M1774; ATR inhibitor 1) is a selective and orally active ATR inhibitor extracted from patent WO2015187451A1, compound I-l, with a Ki value below 1 μΜ[1].
Applications: Cancer-Kinase/protease
Formula: C16H12F2N8O
References: [1]Nadia AHMAD, et al. Radiolabelled derivatives of a 2-amino-6-fluoro-n-[5-fluoro-pyridin-3-yl]- pyrazolo[1,5-a]pyrimidin-3-carboxamide compound useful as atr kinase inhibitor, the preparation of said compound and different solid forms thereof. WO2015187451A1/[2]Lin Li, et al. Non-canonical role for the ataxia-telangiectasia-Rad3 pathway in STAT3 activation in human multiple myeloma cells
CAS Number: 1613200-51-3
Molecular Weight: 370.32
Compound Purity: 99.77
Research Area: Cancer
Solubility: DMSO : 5 mg/mL (ultrasonic)
Target: ATM/ATR