Product Description: UNC10217938A is a 3-deazapteridine analog with strong oligonucleotide enhancing effects. UNC10217938A enhances oligonucleotides effects by modulating their intracellular trafficking and release from endosomes. UNC10217938A also enhances the effects of antisense and siRNA oligonucleotides[1].
References: [1]Yang B, et al. High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides. Nucleic Acids Res. 2015 Feb 27;43(4):1987-96.
CAS Number: 1347749-97-6
Molecular Weight: 456.54
Compound Purity: 99.41
Research Area: Others
Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 80°C)