URB447, CAS 1132922-57-6

Product Description: URB447 is a peripherally restricted CB1 cannabinoid antagonist (IC50: 313 nM and 41 nM for rat CB1 and human CB2 receptor respectively ). URB447 lowers food intake and body-weight gain in mice without entering the brain or antagonizing central CB1-dependent responses. URB447 can be used for research of obesity[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: C25H21ClN2O

References: [1]LoVerme J, et al. Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice. Bioorg Med Chem Lett. 2009 Feb 1;19(3):639-43.

CAS Number: 1132922-57-6

Molecular Weight: 400.90

Compound Purity: 99.5

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Cannabinoid Receptor

• Artikelnummer: MEXHY-122964-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-122964-25
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK