Product Description: Valsartan methyl ester (Compound 3) is a derivative of Valsartan (HY-18204). Valsartan methyl ester is an orally active antagonist for angiotensin II, that inhibits angiotensin II (IC50 of 0.06 μM), angiotensin II-induced pressor response in rabbit aorta (IC50 of 0.068 μM) and angiotensin II-induced pressor response in the pithed rat model (10% inhibition at 10 mg/kg, p.o.)[1].
Applications: Neuroscience-Neuromodulation
Formula: C25H31N5O3
References: [1]Bühlmayer P, et al., Valsartan, a potent, orally active angiotensin II antagonist developed from the structurally new amino acid series[J]. Bioorganic & Medicinal Chemistry Letters, 1994, 4(1): 29-34.
CAS Number: 137863-17-3
Molecular Weight: 449.55
Compound Purity: 99.39
Research Area: Cardiovascular Disease
Solubility: DMSO : 175 mg/mL (ultrasonic)
Target: Angiotensin Receptor
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